Netcare 911 paramedics and other services responded to an accident on Barkley Road in Kimberley last night.
Upon their arrival on scene they found that a motor vehicle had left the roadway and crashed through a wall.
One person tragically lost a life while three others were injured.
The injured patients were treated on scene before they were transported to hospital for further medical care.
Exact detail to the cause of the accident and preceding events will remain the subject of a police investigation.